Systemic Lupus Essay -- Health, Diseases

Systemic lupus erythematosus (SLE) is a fairly common infirmity identified as episodes of inflammation and damage to joints, xdons, and various organs. The most accomplished organs are the heart, lungs, brain, kidneys, blood vessels, and skin. Lupus affects each one-on-one differently and the set up could be mild to severe depending on the individual. SLE is an autoimmune distemper where the bodys immune system attacks the healthy cells and tissues in the body (Ohio State, 2009).The main cause of lupus is unknown, tho there are believed to be many a(prenominal) factors that could contribute to lupus. Lupus is believed to be genetic for many individuals (Ohio State, 2009). If a mother has SLE, her lady friend has a 140 chance of captureing lupus, whereas, her son has a 1250 chance (Leber, 2009). Environmental issues could be present where the cause in the environment is unknown. SLE can also be caused by near medications. The indisposition may be present while taking the m edication, but disappear when the individual stops taking the medication. The majority of people who baffle lupus are women between late teens to forty-five. Females are affected three to ten times more likely than males (Ohio State, 2009). African American women are more likely to develop lupus than Caucasian women (Leber, 2009).Human leukocyte antigens are a concourse of genes on chromosome six. The human leukocyte antigens (HLA) associated with lupus is called DR2 and DR3. A person who has these antigens is very likely to develop lupus, but individuals with different antigens may also develop SLE (Ohio State, 2009). there are many symptoms of SLE and will vary from individual to individual with the disease. Some common symptoms are inflammation of the joints, Raynauds phenomenon1, m... ...ttempt to treat sensible symptoms of SLE as well as the psychological symptoms. HRQoL, disease activity, and disease damage are three different components of lupus and should be measured each for the most accurate results. Measuring the patients quality of career will assist in keeping the patient informed about(predicate) how the disease is affecting them in their daily lives. HRQoL will vary significantly with each individual and is very important to measure patients responses to lupus. Fatigue is a widely influential factor in lupus patients and should be included in quality of life studies (McElhone, 2006). Studies found a mathematical function of defensins in the pathogenesis of SLE (Froy, 2009). Although, when SLE involves major organ, the disease can be put into remission with corticosteroids and immunosuppressive therapy, these treatments can cause toxic results (Ntali, 2009).